发明名称 Apparatus and method for non-invasively detecting diseases that affect structural properties in biological tissues
摘要 Apparatus and methods for spectroscopic analysis of biological tissues to classify an individual as diabetic or non-diabetic, or to determine the probability, progression or level of a disease or medical condition in an individual.
申请公布号 US8989848(B2) 申请公布日期 2015.03.24
申请号 US201113291072 申请日期 2011.11.07
申请人 Freedom Meditech, Inc. 发明人 Rorabaugh Dale A.;Davis Neil M.;Brancaccio Vincent F.;Williams Paul
分类号 A61B5/00;A61B3/117;A61B5/145;A61B5/1455;G01N21/64;G01N21/65 主分类号 A61B5/00
代理机构 DLA Piper LLP (US) 代理人 DLA Piper LLP (US)
主权项 1. An apparatus for determining characteristics of biological tissue or other medium of a subject, comprising: a) means for illuminating the medium with electromagnetic radiation directed into the medium, the means for illuminating comprising a blue LED light source, thereby causing the medium to react with a first action selected from the group consisting of reflecting, backscattering, transmitting, and emitting responsive radiation and a second action selected from the same group excluding the first action; b) a detector for collecting the responsive radiation; c) an optical filter connected to the detector, for separating the collected radiation into a plurality of components, wherein the plurality of components comprises a fluorescent component; d) a processor operable to (i) measure the intensity of each of the separated plurality of components and (ii) determine a mathematical relationship between the separated plurality of components; e) a LED fixation tube for guiding the subject to self-align itself along an axis; f) a lens, optically responsive to the light from the light source, for focusing the light; and g) a lens system, optically responsive to the focused light, having a focus, and defining an aperture at its focus of less than approximately 1 cm, wherein the wavelength of the fluorescent component of the radiation is selected from the group consisting of between approximately 465-500 nm and 520-600 nm.
地址 San Diego CA US