Needleless delivery systems

摘要

A method of treating a prostate condition, including the steps of providing a needleless injector that includes a body at a proximal end, an injection shaft extending from the body to a distal end of the injection shaft, an injection orifice at the distal end of the injection shaft and positioned for fluid ejection in a lateral direction relative to a longitudinal axis of the injection shaft, a pressure source in communication with the fluid chamber, and an extendable tissue tensioner located at the distal end of the injection shaft proximal to the injection orifice; inserting the injection shaft into a urethra so the injection orifice is located within the prostatic urethra; actuating the tissue tensioner to contact urethral tissue, and injecting fluid from the injection orifice into the prostate.

主权项

1. A method of treating a prostate condition, the method comprising the steps of:
preparing a needleless injector for insertion into a patient, the injector comprising:
a body at a proximal end;a first shaft extending distally from the body and having a distal end;an injection shaft extending from the body and comprising a distal end, the injection shaft being moveable along a length of the first shaft, wherein the distal end of the injection shaft is proximal to the distal end of the first shaft;an injection orifice at the distal end of the injection shaft in fluid communication with a fluid chamber at the proximal end of the body, the injection orifice being positioned for fluid ejection in a lateral direction relative to a longitudinal axis of the injection shaft and located within the first shaft, wherein the injection orifice is axially moveable along the longitudinal axis;
a pressure source in communication with the fluid chamber;and an extendable tissue tensioner located at the distal end of the injection shaft proximal to the injection orifice; inserting the injection shaft into a urethra so the injection orifice is located within the prostatic urethra, actuating the tissue tensioner to contact urethral tissue, and injecting fluid from the injection orifice directly onto a prostate tissue surface.