Ionization method, ion producing device and uses of the same in ion mobility spectrometry

摘要

A method for ionizing, using pulses of ionization radiation, an analyte to be examined by way of ion mobility spectrometry using a pulse sequence is modulated with a known time-variable impression pattern is provided. An ionization device for carrying out the method and an ion mobility spectrometry method and an ion mobility spectrometry device that use the ionization method and/or the ionization device are also provided.

主权项

1. An ionization method, comprising:
generating a pulse sequence of ionizing radiation that is modulated by a previously known time-variable impression pattern, wherein the pulse sequence of ionizing radiation is modulated in a binary manner, wherein previously known time-variable impression pattern is a quasi-random, pseudo-random, or non-repetitive impression pattern; and ionizing an analyte to be examined using the generated pulse sequence of ionizing radiation, wherein the pulse sequence of ionizing radiation has a pulse frequency and is modulated at time intervals by an interval frequency, and wherein the pulse frequency and interval frequency are greater than 1 kHz and less than 500 MHz.