| 主权项 |
1. A medical composition configured for administering by direct transport of at least one drug directly into lung regions of a patient during inhalation, comprising:
a carrier for at least one active substance, wherein the carrier is at least one semifluorinated alkane of the type RFRH, wherein RF is a straight chain or branched perfluoro alkyl group and RH is a straight chain or branched saturated hydrocarbon group, and wherein the composition comprises a solution at room temperature and wherein at least part of the carrier vaporizes at temperatures in the lung regions of a patient; wherein the length of each RF and RH segment is 2 to 20 carbon atoms, the at least one active substance being dispersed in the carrier as a colloid or molecular dispersion with a particle size of less than 100 nm at a concentration at which the active substance is configured to remain deposited when the semifluorinated alkane is exhaled; and wherein the at least one active substance is selected from the group consisting of mucolytic and antispasmodic, bronchial-enlarging, surface-active, antiinflammatory and antiischaemic substances, or wherein the at least one active substance is selected from the group consisting of the cytostatic agents, antiviral agents, bacteriostatic agents, antiasthmatic agents, antihistamines, antiinflammatory, bronchial-enlarging, circulation-enhancing medicaments, proteins, growth factors, peptides, and vitamins. |
