发明名称 |
METHOD FOR ATOMIC LAYER DEPOSITION |
摘要 |
An atomic layer deposition method is disclosed for preparing polypeptides. The method comprises providing a solid-phase support comprising a reactive amine monolayer in an atomic layer deposition (ALD) chamber. The solid-phase support is contacted with a first protected amino acid substituted with a protecting group by atomic layer deposition, wherein the protecting group is bonded to a non-side chain amino group of the protected amino acid. A carboxylic acid group of the first protected amino acid is reacted with the reactive amine monolayer, thereby coupling the first protected amino acid to the solid- phase support to produce a coupled-product. |
申请公布号 |
WO2015038919(A1) |
申请公布日期 |
2015.03.19 |
申请号 |
WO2014US55430 |
申请日期 |
2014.09.12 |
申请人 |
STC. UNM |
发明人 |
JIANG, YING-BING;CECCHI, JOSEPH, L.;FU, YAQIN;BRINKER, C., JEFFREY |
分类号 |
C23C16/455;C23C16/52 |
主分类号 |
C23C16/455 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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