INFECTIOUS LARYNGOTRACHEITIS VIRUS (ILTV) VACCINE USING RECOMBINANT NEWCASTLE DISEASE VIRUS VECTOR

摘要

In this study, for the first time, protective efficacy of gD against ILTV challenge was evaluated. Immunization with recombinant Newcastle disease virus expressing ILTV gD induced a higher level of neutralizing antibodies and offered complete protection to chickens against lethal ILTV challenge. Uses of recombinant NDV as a vaccine vector are also described.