| 发明名称 |
COMPOUNDS USEFUL AS RAF KINASE INHIBITORS |
| 摘要 |
The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases. |
| 申请公布号 |
US2015080568(A1) |
申请公布日期 |
2015.03.19 |
| 申请号 |
US201414444007 |
申请日期 |
2014.07.28 |
| 申请人 |
Millennium Pharmaceuticals, Inc. ;Sunesis Pharmaceuticals, Inc. |
发明人 |
Chen Weirong;Lane Benjamin;Peng Hairuo |
| 分类号 |
C07D487/04;C07D413/14;C07D417/14 |
主分类号 |
C07D487/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound of formula II-vi-a: wherein: A− is a suitable chiral anion; Cy1 is an optionally substituted 5-6 membered saturated, partially unsaturated, or aromatic ring having 1-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur; and Cy2 is an optionally substituted 5-10 membered saturated, partially unsaturated, or aromatic monocyclic or bicyclic ring having 0-4 heteroatoms, independently selected from nitrogen, oxygen, or sulfur. |
| 地址 |
Cambridge MA US |
