MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF
摘要
Methods and compositions are provided for extending the half-life of a therapeutic agent. One or more half-life extending moieties may be attached to a therapeutic agent, thereby extending the half life of the therapeutic agent. The modified therapeutic agents (mTAs) comprising one or more half-life extending moieties attached to a therapeutic agent may be used to treat a disease or condition in a subject in need thereof.
申请公布号
CA2924109(A1)
申请公布日期
2015.03.19
申请号
CA20142924109
申请日期
2014.09.12
申请人
THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH;THE SCRIPPS RESEARCH INSTITUTE
发明人
SHEN, WEIJUN;SCHULTZ, PETER G.;MUPPIDI, AVINASH;CRAMERI, ANDREAS;AHMAD, INSHA;YANG, PENGYU