SYSTEMS AND METHODS FOR PROCESSING CELLS

摘要

The present invention efficiently and cost-effectively extracts and collects cells from a tissue. The inventors have discovered that the tissue can be effectively fragmented and the resulting cells can be purified using a system or kit with multiple components. An advantage of the present invention is that tissue processing takes place in a closed system such that sterility can be maintained throughout the process, even if certain components are removed during processing, for example through the use of valves, clamps, and heat seals. Furthermore, any or all of the steps can be automated or manually accomplished, according to the specific needs of the application or the user.

主权项

1. A tissue mincing tool comprising:
a compartment for a tissue sample; a solid member automatedly translatable within the compartment; a cutting surface at one end of the compartment; and a sterile, sealed container, wherein the cutting surface separates the compartment from the sterile, sealed container, such that a tissue sample that is pressed, via an automated translation of the solid member, into contact with and through the cutting surface is deposited as a minced tissue within the sterile, sealed container.