发明名称 |
USE OF GLYCOSAMINOGLYCANS TO REDUCE NON-SPECIFIC BINDING IN IMMUNOASSAYS |
摘要 |
<p>An immunoassay reagent is provided which comprises an analyte binding agent in a diluent, and a glycosaminoglycan in an amount sufficient to reduce non-specific binding in an assay of a sample for the analyte. Provided is such an immunoassay reagent in which the analyte is troponin I, the analyte binding agent is a biotinylated anti-troponin I antibody, and the glycosaminoglycan is chondroitin sulfate. A sample composition is also provided which comprises a sample to be assayed for the presence of an analyte, an analyte binding agent, and a glycosaminoglycan other than heparin. Further provided is a method of detecting an analyte in a sample, in which non-specific binding is reduced in the method using a glycosaminoglycan.</p> |
申请公布号 |
AU2015200977(A1) |
申请公布日期 |
2015.03.19 |
申请号 |
AU20150200977 |
申请日期 |
2015.02.26 |
申请人 |
ORTHO-CLINICAL DIAGNOSTICS, INC. |
发明人 |
SANKARAN, BANUMATHI;SULLIVAN, SHERYL S.;HAYNES, DARRELL C.;HOSIMER, PHILIP C.;YEARWOOD, GRAHAM |
分类号 |
G01N33/53 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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