| 发明名称 |
DNA SEQUENCE AND PREPARATION OF GRASS POLLEN ALLERGEN PHL P4 BY RECOMBINANT METHODS |
| 摘要 |
The present invention relates to the preparation and use of recombinant variants of group 6 allergens of the Poaceae (true grasses), which are characterised by reduced IgE reactivity compared with known wild-type allergens and at the same time substantially retained reactivity with T-lymphocytes. |
| 申请公布号 |
US2015079120(A1) |
申请公布日期 |
2015.03.19 |
| 申请号 |
US201414550370 |
申请日期 |
2014.11.21 |
| 申请人 |
Merck Patent GmbH |
发明人 |
FIEBIG Helmut;NANDY Andreas;SUCK Roland;CROMWELL Oliver;PETERSEN Arnd;BECKER Wolf-Meinhard |
| 分类号 |
C07K14/415;A61K45/06;A61K39/39;A61K39/36;A61K31/7088 |
主分类号 |
C07K14/415 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A DNA molecule corresponding to a nucleotide sequence selected from a group consisting of SEQ ID NO 1, SEQ ID NO 3 and SEQ ID NO 5. |
| 地址 |
Darmstadt DE |
