C DIFF PROTEASE

摘要

The invention relates to a peptide comprising the amino acid sequence A/P- A/P-V/P/I/C/T-P as a substrate for the protease CD2830 of Clostridium difficile. The invention further relates to kit or device comprising the peptide for determining the presence of Clostridium difficile in a sample and for identifying an agent that is capable of modulating protease activity of CD2830. The invention further relates to a composition, preferably a pharmaceutical composition, comprising an inhibitor of the protease activity of CD2830.