发明名称 |
ACTIVATABLE ANTIBODIES THAT BIND EPIDERMAL GROWTH FACTOR RECEPTOR AND METHODS OF USE THEREOF. |
摘要 |
The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to epidermal growth factor receptor (EGFR), and to methods of making and using these anti- EGFR activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications. |
申请公布号 |
MX2014013041(A) |
申请公布日期 |
2015.03.19 |
申请号 |
MX20140013041 |
申请日期 |
2013.04.26 |
申请人 |
CYTOMX THERAPEUTICS, INC. |
发明人 |
HENRY BERNARD LOWMAN;LUC ROLAND DESNOYERS;SHOUCHUN LIU;JAMES WILLIAM WEST;JASON GARY SAGERT;OLGA VASILJEVA;ELIZABETH -EDNA MARY MENENDEZ |
分类号 |
A61K39/00;C07K16/28;C12P21/08 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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