| 发明名称 |
NON-CATALYTIC DOMAIN TARGETS IN MATRIX METALLOPROTEASE PROTEINS FOR CANCER THERAPIES |
| 摘要 |
The present invention provides compositions and methods for inhibiting MMPs, especially MMP-3, MMP-9 and MMP-14. The invention relates to the field of diagnostic and prognostic methods of human cancers, especially breast cancer and the field of matrix metalloproteases, as targets for diagnostics and therapeutics. |
| 申请公布号 |
US2015079071(A1) |
申请公布日期 |
2015.03.19 |
| 申请号 |
US201314094702 |
申请日期 |
2013.12.02 |
| 申请人 |
Bissell Mina J.;Nelson Celeste M.;Mori Hidetoshi;Correia Ana Luisa Pinto;Chen Emily |
发明人 |
Bissell Mina J.;Nelson Celeste M.;Mori Hidetoshi;Correia Ana Luisa Pinto;Chen Emily |
| 分类号 |
C07K16/40;C12N15/115;C12N15/113 |
主分类号 |
C07K16/40 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for inhibiting matrix metalloproteinase (MMP) proteins comprising contacting a cell with a compound that binds to a non-catalytic MMP domain and inhibits a biological effect. |
| 地址 |
Berkeley CA US |
