| 摘要 |
An antiseptic composition comprising a multivalent cationic antiseptic present in an amount of 0.05 to 0.5 percent based upon the ready to use composition; an anionic compound which is water soluble in an amount of at least 0.1 grams in 100 grams water at 23°C, wherein the anionic compound is present at a concentration which would result in precipitation of the multivalent cationic antiseptic in the composition without a solubilizing surfactant present; and a solubilizing surfactant selected from the group consisting of zwitterionic surfactants, amine oxide surfactants, micelle-forming nonionic surfactants, and combinations thereof; wherein the solubilizing surfactant is present in sufficient amount to prevent the precipitation; and wherein the composition, with the antiseptic, surfactant and anionic compound combined with each other, is free of precipitate according to Test Method A; and without the surfactant, the composition contains a precipitate according to Test Method A; an oral care kit comprising the antiseptic composition and a delivery device; methods of decolonizing mucosal tissue, decontaminating wound tissue, and pretreating medical devices, comprising contacting the tissue or medical device with the antiseptic composition, and methods of preparing the compositions are provided. |
