发明名称 |
MULTIPLEXED IMAGING OF TISSUES USING MASS TAGS AND SECONDARY ION MASS SPECTROMETRY |
摘要 |
A method of generating a high resolution two-dimensional image of a sample comprising cells and extracellular structures is provided. In certain embodiments, the method comprises: labeling a sample with at least one mass tag, thereby producing a labeled sample; scanning the sample with a secondary ion mass spectrometer (SIMS) ion beam to generate a data set that comprises spatially-addressable measurements of the abundance of the mass tag across an area of the sample; and outputting the data set. In many embodiments, the data set contains the identity and abundance of the mass tag. A system for performing the method is also provided. |
申请公布号 |
CA2924284(A1) |
申请公布日期 |
2015.03.19 |
申请号 |
CA20142924284 |
申请日期 |
2014.09.11 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
BENDALL, SEAN C.;NOLAN, GARRY P.;ANGELO, ROBERT M. |
分类号 |
B01D59/44 |
主分类号 |
B01D59/44 |
代理机构 |
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