| 主权项 |
1. A method of inhibiting angiogenesis in a biological system, the method including administering to the biological system an effective amount of a steroid saponin, wherein the steroid saponin is selected from the group consisting of deltonin (diosgenin Rha2, [Glc4], Glc), dioscin (diosgenin Rha2, [Rha4], Glc), and prosapogenin A (diosgenin Rha2, Glc), wherein the angiogenesis in the biological system is angiogenesis associated with angiofibroma, corneal neovascularisation, retinal/choroidal neovascularization, diabetic retinopathy, age-related macular degeneration, arteriovenous malformations, arthritis, rheumatoid arthritis, osteoarthritis, psoriatic arthritis, lupus, connective tissue disorders, Osler-Weber syndrome, atherosclerotic plaques, psoriasis, pyogenic granuloma, retrolental fibroplasias, scleroderma, granulations, hemangioma, trachoma, haemophilic joints, vascular adhesions, hypertrophic scars, diseases or conditions associated with acute or chronic inflammation, diseases or conditions associated with chronic inflammation of the lung, asthma, sarcoidosis, inflammatory bowel diseases, Crohn's disease or ulcerative colitis. |
