| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a high-purity texaphyrin metal complex, a method for making the complex, and a method for using the complex to treat a disease or the like including cancer and atherosclerosis. <P>SOLUTION: The texaphyrin metal complex has anticancer activity and is represented by formula 1 (wherein: M is a trivalent metal cation such as Gd<SP POS="POST">+3</SP>; each X is OH<SP POS="POST">-</SP>or the like; R<SB POS="POST">3</SB>to R<SB POS="POST">8</SB>are independently H, OH or the like; R<SB POS="POST">1</SB>and R<SB POS="POST">2</SB>are independently H or 1 to 6C alkyl; and each x is independently selected from 2 to 6). <P>COPYRIGHT: (C)2013,JPO&INPIT</p> |
