发明名称 |
Methods for producing antibodies from plasma cells |
摘要 |
<p>The invention relates to methods of producing antibodies, including monoclonal antibodies, comprising culturing a limited number of plasma cells. It also relates to methods of identifying antibodies by performing assays on the antibodies produced by the cultured plasma cells to determine their function, binding specificity, epitope specificity, and/or their ability to neutralize a toxin or a pathogen. The invention also relates to antibodies and antibody fragments produced by the methods of the invention as well as methods of using the antibodies and antibody fragments</p> |
申请公布号 |
EP2848630(A1) |
申请公布日期 |
2015.03.18 |
申请号 |
EP20140003359 |
申请日期 |
2009.10.22 |
申请人 |
INSTITUTE FOR RESEARCH IN BIOMEDICINE |
发明人 |
LANZAVECCHIA, ANTONIO;JARROSSAY, DAVID |
分类号 |
C07K16/00;C07K16/10;C07K16/12;C12N5/0781 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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