| 摘要 |
The invention relates to a compound of formula (I), where: n is an integer equal to 0 or 1; R1 is, when n=0, an alkyl chain having 3 to 6 carbon atoms, an alkenyl chain, alkylene, a linear hydroxyalkyl chain having 2 to 6 carbon atoms, the hydroxyl function optionally being protected or the oxygen of said function being substituted so as to form a leaving group, a halogenoalkyl chain having 2 to 6 carbon atoms, the halogen optionally being radioactive, or a fluoromethyl group, the fluorine optionally being radioactive, and when n=1, a monohydroxyalkyl chain having 1 to 6 carbon atoms, the hydroxyl function, at the terminal position, optionally being protected or the oxygen of said function being substituted so as to form a leaving group, or monohalogenoalkyl having 1 to 6 carbon atoms, the halogen at the terminal position optionally being radioactive, wherein the halogen is not bromine; P1 is, when n=0, hydrogen or a group protecting the hydroxyl function, identical or different, when n=1 and R1 is a monohydroxyalkyl chain, hydrogen or a group protecting the hydroxyl function, identical or different, and when n=1 and R1 is a monohalogenalkyl chain, hydrogen or a group protecting the hydroxyl function, identical or different; Y1 is, when n=0, an OP1 group, where P1 is as defined above, or, when n=1, a hydrogen atom, with the exception of the non-radiolabeled 2-fluoromethyl-myo-inositol compounds for which P1, identical or different, is a hydrogen atom or a benzyl protecting group, and to the use thereof as a drug. |
