| 发明名称 |
THERAPEUTIC AGENTS |
| 摘要 |
<p>A compound of the formula (I): wherein R1, R2, R3, R4, Ar, A, n and m are defined herein, is disclosed as a GlyT1 inhibitor; pharmaceutical compositions containing the compound of the formula (I) are also disclosed as are their use in medicine, for example in the treatment of schizophrenia.</p> |
| 申请公布号 |
EP1899294(B1) |
申请公布日期 |
2015.03.18 |
| 申请号 |
EP20060744198 |
申请日期 |
2006.06.13 |
| 申请人 |
MERCK SHARP & DOHME LIMITED |
发明人 |
BLACKABY, WESLEY PETER;HUSCROFT, IAN THOMAS;KEOWN, LINDA ELIZABETH;LEWIS, RICHARD THOMAS;RAUBO, PIOTR ANTONI;STREET, LESLIE JOSEPH;THOMSON, CHRISTOPHER GEORGE;THOMSON, JOANNE |
| 分类号 |
C07D249/04;A61K31/10;A61K31/35;A61K31/397;A61K31/40;A61K31/4196;A61K31/435;A61P25/18;C07C317/32;C07D205/04;C07D207/08;C07D207/09;C07D211/26;C07D211/28;C07D211/60;C07D213/40;C07D249/12;C07D295/067;C07D309/04;C07D401/12 |
主分类号 |
C07D249/04 |
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