Image-guided therapy of a tissue

摘要

Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an operator of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.

主权项

1. A system for effecting treatment to a tissue, comprising:
a motorless drive mechanism that is compatible with and can operate within an operational field of a medical imaging system to image the tissue without substantially disrupting imaging performed by the medical imaging system, the motorless drive mechanism including a holder to hold a treatment device to treat the tissue, and a first wire translation mechanism that couples one or more wires to the holder, such that a translation of the one or more wires effects one or more of a longitudinal displacement of the holder and a rotation of the holder; a base unit that is coupled to the motorless drive mechanism by the one or more wires, the base unit including a second wire translation mechanism to translate the one or more wires; an electronic controller including an input interface to receive position control signals for setting a position of the treatment device, and an output interface that is coupled to the second wire translation mechanism of the base unit, such that the output interface effects movements of the second wire translation mechanism to translate the one or more wires based on the position control signals received by the input interface to effect movements of the first wire translation mechanism, such that one or more of the longitudinal displacement of the holder and the rotation of the holder are effected based on the position control signals received by the input interface; an energy emission probe as the treatment device, wherein the probe generates a plurality of different output patterns, including, with respect to a longitudinal axis of the probe, a symmetrical output pattern and an asymmetrical output pattern; an energy source to generate energy for the probe; and a workstation adapted to transmit the position control signals to the electronic controller, and to transmit energy control signals to the energy source, wherein the workstation is adapted to process a sequence of the position and energy control signals to:
move the holder to a first position and effect a symmetrical treatment to a first portion of the tissue that coincides with the first position with the probe, andmove the holder to a second position and effect an asymmetrical treatment to a second portion of the tissue that coincides with the second position with the probe after the symmetrical treatment.