| 发明名称 | Aegyptin and uses thereof | ||
| 摘要 | The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel biological tools, prophylactics, therapeutics, diagnostics, and methods of use of the foregoing are also disclosed. | ||
| 申请公布号 | US8980859(B2) | 申请公布日期 | 2015.03.17 |
| 申请号 | US201313746631 | 申请日期 | 2013.01.22 |
| 申请人 | The United States of America, as represented by the Secretary, Department of Health & Human Services;The Regents of the University of California | 发明人 | Calvo Eric;Marinotti Osvaldo;Ribeiro Jose M. C.;Francischetti Ivo M. |
| 分类号 | A61K48/00;C07K14/435;A61K38/49;A61K45/06;A61K38/00 | 主分类号 | A61K48/00 |
| 代理机构 | Swanson & Bratschun, L.L.C. | 代理人 | Swanson & Bratschun, L.L.C. |
| 主权项 | 1. A method of disrupting platelet adhesion in a subject comprising: identifying a subject in need of a molecule that disrupts platelet adhesion and providing said subject with a therapeutically effective amount of said molecule, wherein said molecule is a nucleic acid encoding an Aegyptin polypeptide or fragment thereof. | ||
| 地址 | Washington DC US | ||