主权项 |
1. A compound of Formula (IV), wherein R2 is C1-C4 alkyl; R6 is C1-C6 alkyl; R7 is C1-C6 alkyl, CH2-Phenyl, CH2OR19 or CH2OCOR20, wherein R19 is alkyl, R20 is phenyl, or CH2-Phenyl; R9 is C1-C6 alkyl; R10° is H, OH, O-alkyl or O-acetyl; f is 1 or 2; R11 is a group of the Formula (II) wherein R15 is a group of the formula wherein R21 is H, halogen, OH, NO2 NH2, CN, alkyl, heteroalkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, alkyloxy, alkyl amino or dialkyl amino; R16 is H or CH3; R17 is CO2H, CO2R18, CONHNH2, OH, NH2, SH or an optionally substituted heteroalkyl or heterocycloalkyl group, wherein R18 is an optionally substituted alkyl, heteroalkyl or heterocycloalkyl group; and p is 0, 1, 2 or 3; or a pharmacologically acceptable salt, a solvate, a hydrate or a pharmacologically acceptable formulation thereof. |