发明名称 |
Process to avoid inhibition of acetogens by CO |
摘要 |
A process is provided for fermenting CO-containing gaseous substrates. The process is effective for decreasing lag times and maintaining a culture in steady state by controlling CO concentration and minimizing effects of high or low CO concentrations during fermentation. The process includes providing syngas to a first fermentation zone, fermenting the syngas, and determining a CO concentration in a fermentation medium in the first fermentation zone. If the CO concentration in fermentation medium in the first fermentation zone has a calculated value of about 0.12 mM or greater, then at least a portion of the syngas being provided to the first fermentation zone is provided to one or more subsequent fermentation zones in an amount effective for providing a calculated CO concentration in any subsequent fermentation zone of about 0.12 mM or less. |
申请公布号 |
US8980575(B2) |
申请公布日期 |
2015.03.17 |
申请号 |
US201314018487 |
申请日期 |
2013.09.05 |
申请人 |
Ineos Bio SA |
发明人 |
Senaratne Ryan |
分类号 |
C12Q1/02;B01D51/00 |
主分类号 |
C12Q1/02 |
代理机构 |
Ineos USA LLC |
代理人 |
Ineos USA LLC |
主权项 |
1. A method for reducing growth inhibition by carbon monoxide (CO) of microbes in fermentation, comprising:
a) providing syngas to a first fermentation zone; b) fermenting the syngas; and c) determining the CO concentration in the fermentation medium in the first fermentation zone, wherein if the CO concentration in the fermentation medium in the first fermentation zone has a calculated value of 0.12 mM or greater, then at least a portion of the syngas being provided to the first fermentation zone is provided to one or more subsequent fermentation zones in an amount effective for providing a calculated CO concentration in the first fermentation zone of at least 0.12 mM or less. |
地址 |
Rolle CH |