Recombinant microorganism and method for producing aliphatic polyester using the same

摘要

Aliphatic polyester productivity is improved for production of aliphatic polyester using a recombinant microorganism. A recombinant microorganism prepared by introducing a gene encoding a protein having activity of converting lactic acid to lactic-acid CoA and a gene encoding a protein having activity of synthesizing polyhydroxyalkanoate using hydroxyacyl CoA as a substrate into a host microorganism is cultured and then aliphatic polyester is recovered from the medium.

主权项

1. A recombinant microorganism, which is prepared by introducing: a gene encoding a protein having activity of converting lactic acid to lactic-acid CoA; and one or more genes encoding a protein(s) having activity of synthesizing polyhydroxyalkanoate using hydroxyacyl CoA as a substrate into a host microorganism, wherein one of said one or more genes that encode a protein having activity of synthesizing polyhydroxyalkanoate using hydroxyacyl CoA as a substrate is an Alcanivorax borkumensis-derived gene encoding a protein that comprises the amino acid sequence shown in SEQ ID NO: 6.