发明名称 |
BIS(TRIFLUOROMETHYL)ZINC DMPU COMPLEX, MANUFACTURING METHOD THEREOF AND MANUFACTURING METHOD OF TRIFLUOROMETHYL GROUP-CONTAINING COMPOUND USING THE SAME |
摘要 |
<p>PROBLEM TO BE SOLVED: To provide a bis(trifluoromethyl)zinc DMPU complex stable under room temperature and useful as a reaction reagent, a manufacturing method thereof and a manufacturing method of a trifluoromethyl group-containing compound using the same.SOLUTION: A method of obtaining a trifluoromethyl group-containing compound by reacting with a substituted aromatic iodide under a copper (I) catalyst after obtaining a bis(fluoromethyl)zinc DMPU complex represented by the formula (1) (CF)Zn (DMPU)(1), where DMPU represents N,N'-dimethyl propylene urea, by reacting dialkyl zinc, trifluoromethyl halide and N,N'-dimethyl propylene urea in an organic solvent, then filtration or solvent leaving removal of precipitate.</p> |
申请公布号 |
JP2015048322(A) |
申请公布日期 |
2015.03.16 |
申请号 |
JP20130180007 |
申请日期 |
2013.08.30 |
申请人 |
TOKYO INSTITUTE OF TECHNOLOGY;TOSOH F-TECH INC |
发明人 |
MIKAMI KOICHI;NAKAMURA YUZO;NEGISHI KAZUYUKI;AIKAWA KOSUKE |
分类号 |
C07F3/06;C07C41/22;C07C43/247;C07C67/307;C07C69/76;C07C201/12;C07C205/11;C07C253/30;C07C255/50;C07D213/26;C07D213/61;C07D233/32;C07D241/12 |
主分类号 |
C07F3/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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