摘要 |
<p>PROBLEM TO BE SOLVED: To provide a method for producing a strongly metastatic human cancer cell line from a non-metastatic or weakly metastatic human cancer cell line, and to provide a strongly metastatic human cancer cell line obtained by the method.SOLUTION: The invention provides a strongly metastatic human cancer cell line obtained by co-implantation of non-metastatic or weakly metastatic human cancer cells and carcinoma-associated fibroblasts into an immunodeficiency nonhuman animal to proliferate in the body of the immunodeficiency nonhuman animal concerned.</p> |