发明名称 PEPTIDE DERIVATIVES AND USE THEREOF AS CARRIERS FOR MOLECULES IN THE FORM OF CONJUGATES
摘要 The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorize molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB).
申请公布号 HRP20141139(T1) 申请公布日期 2015.03.13
申请号 HR2014P001139T 申请日期 2014.11.24
申请人 VECT-HORUS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITÉ D'AIX-MARSEILLE 发明人 KHRESTCHATISKY, MICHEL;DAVID, MARION;MOLINO, YVES;VLIEGHE, PATRICK
分类号 C07K7/08;A61K38/04;C07K14/775 主分类号 C07K7/08
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