发明名称 |
FUCOSYLATION-DEFICIENT CELLS |
摘要 |
A cell as provided that expresses a GDP-4-keto-6-deoxy-mannose-3,5-epimerase-4-reductase (FX) protein with a modification, wherein the cell lacks or substantially lacks the ability to fucosylate a glycoprotein at a first temperature, but does not lack or does not substantially lack the ability to fucosylate the glycoprotein at a second temperature. Methods for making antigen binding proteins are also provided which use the cell. |
申请公布号 |
HK1198180(A1) |
申请公布日期 |
2015.03.13 |
申请号 |
HK20140112533 |
申请日期 |
2012.05.07 |
申请人 |
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发明人 |
CHEN, GANG;BURAKOV, DARYA;FANDL, JAMES, P. |
分类号 |
C12N;C07K;C12P |
主分类号 |
C12N |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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