发明名称 |
Colagenasa de fusión a la que se une una marca de afinidad, y método para producir la misma |
摘要 |
<p>A fusion collagenase in which an affinity tag is added to the carboxyl terminal of a collagenase was expressed as a recombinant protein. It was found that a collagenase having a collagen-binding domain can be selectively collected by purifying the obtained fusion collagenase by affinity chromatography.</p> |
申请公布号 |
ES2531402(T3) |
申请公布日期 |
2015.03.13 |
申请号 |
ES20090827488T |
申请日期 |
2009.11.06 |
申请人 |
MEIJI SEIKA PHARMA CO., LTD.;TOHOKU UNIVERSITY |
发明人 |
FUKUSHIMA, TAKAYOSHI;YOKOYAMA, KENGO;MURASHIMA, KOICHIRO;GOTO, MASAFUMI;YAMAGATA, YOUHEI |
分类号 |
C12N15/00;C07K14/78;C07K19/00;C12N1/21;C12N5/071;C12N9/52;C12N15/09 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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