PHOSPHONIC ACID DERIVATES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS

摘要

THE INVENTION RELATES TO 2-PHENYL-PYRIMIDINE DERIVATIVES CONTAINING A PHOSPHONIC ACID MOTIF AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS IN THE TREATMENT AND/OR PREVENTION OF PERIPHERAL VASCULAR, OF VISCERAL-, HEPATIC- AND RENAL-VASCULAR, OF CARDIOVASCULAR AND OF CEREBROVASCULAR DISEASES OR CONDITIONS ASSOCIATED WITH PLATELET AGGREGATION, INCLUDING THROMBOSIS IN HUMANS AND OTHER MAMMALS.