发明名称 PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS
摘要 The present invention relates to pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment and/or prevention of a proliferation disorder, a cancer, a tumor, an inflammatory disease, an autoimmune disease, psoriasis, dry eye or an immunologically related disease, and in some embodiments diseases or disorders related to the dysregulation of kinase such as, but not limited to, EGFR (including HER), Alk, PDGFR, BLK, BMX/ETK, FLT3(D835Y), ITK, TEC, TXK, BTK, or JAK, and the respective pathways.
申请公布号 WO2015006754(A3) 申请公布日期 2015.03.12
申请号 WO2014US46442 申请日期 2014.07.11
申请人 ACEA BIOSCIENCES INC. 发明人 XU, XIAO;WANG, XIAOBO;MAO, LONG;ZHAO, LI;XI, BIAO
分类号 C07D417/12;A61K31/506;A61P35/00;C07D239/545;C07D239/553;C07D403/12;C07D473/18;C07D487/04;C07D519/00 主分类号 C07D417/12
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