发明名称 |
ENCAPSULATED CELLS FOR HORMONE REPLACEMENT THERAPY |
摘要 |
A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition. The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described. |
申请公布号 |
WO2015034825(A1) |
申请公布日期 |
2015.03.12 |
申请号 |
WO2014US53705 |
申请日期 |
2014.09.02 |
申请人 |
WAKE FOREST UNIVERSITY HEALTH SCIENCES |
发明人 |
OPARA, EMMANUEL, C.;YOO, JAMES J.;SAUL, JUSTIN M.;SIVANANDANE, SITTADJODY;ATALA, ANTHONY |
分类号 |
A61K9/50 |
主分类号 |
A61K9/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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