发明名称 |
THERMALLY STABLE VACCINE FORMULATIONS AND MICRONEEDLES |
摘要 |
Formulations and methods are provided for stabilizing antigens in dry solid vaccines. One aspect relates to dry solid formulations of influenza vaccines including one or more excipients identified as imparting stability to influenza antigens. Another aspect relates to dry solid formulations of measles vaccines including one or more excipients identified as imparting stability to a measles antigen. The formulations may be in a form suitable for reconstitution in a physiologically acceptable liquid vehicle to form an injectable solution or suspension for administration to a patient or in the form of dissolvable microneedles or coated microneedles. |
申请公布号 |
WO2015034924(A1) |
申请公布日期 |
2015.03.12 |
申请号 |
WO2014US53902 |
申请日期 |
2014.09.03 |
申请人 |
GEORGIA TECH RESEARCH CORPORATION |
发明人 |
MISTILIS, MATTHEW JOSEPH;EDENS, WILLIAM CHRISTOPHER;BOMMARIUS, ANDREAS SEBASTIAN;PRAUSNITZ, MARK |
分类号 |
A61K39/12;A61K39/145;A61K39/165;C12N7/01 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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