发明名称 COMPOUND HAVING CELL PROLIFERATION-INHIBITING ACTIVITY, PHARMACEUTICAL COMPOSITION, AND SCREENING METHOD
摘要 <p>[Problem] The purpose of the present invention is to develop a pharmaceutical composition that is for malignant tumor treatment and/or prevention and that by using a compound that is normally present in vivo and affects a cellular signal transduction system, is capable of inhibiting proliferation or of killing only tumor cells while having little effect on normal cells, tissue and organs and that has no side effects and is highly safe. [Solution] Provided is a pharmaceutical composition that is for malignant tumor treatment and/or prevention and that contains the effective dose of the compound represented by formula 1 or a pharmaceutically acceptable salt thereof. In formula 1, X is O or S, n is 0, 1, or 2, m is an integer of 0 to 5, 1 is 0, 1 or 2, R is H and the like, R1 is H and the like, R2 is H and the like, R3 is F and the like, and W is a heterocycle or derivative thereof.</p>
申请公布号 WO2015034038(A1) 申请公布日期 2015.03.12
申请号 WO2014JP73456 申请日期 2014.09.05
申请人 WASEDA UNIVERSITY;FRONTIER COMPANY, LTD. 发明人 KIKUTA, TOSHITERU;NAMIKI, HIDEO
分类号 C07H19/073;A61K31/475;A61K31/7068;A61K31/7072;A61K45/00;A61P35/00;C07H19/10;C07H19/11;C07H19/20 主分类号 C07H19/073
代理机构 代理人
主权项
地址