| 主权项 |
1. A method for reducing scar formation, comprising administering to an individual in need thereof an amount effective to reduce scar formation of a polypeptide comprising a sequence according general formula I:
X1-A(X2)APLP-X3 wherein X1 is 0-14 amino acids of the sequence of heat shock protein 20 between residues 1 and 14 of SEQ ID NO: 298; X2 is selected from the group consisting of S, T, Y, D, B, hydroxylysine, hydroxyproline, phosphoserine analogs and phosphotyrosine analogs; and X3 is selected from the group consisting of (a) 0-140 amino acids of heat shock protein 20 between residues 21 and 160 of SEQ ID NO:298; and (b) 0, 1, 2, or 3 amino acids of a sequence of genus Z1-Z2-Z3, wherein Z1 is selected from the group consisting of G and D; Z2 is selected from the group consisting of L and K; and Z3 is selected from the group consisting of S, T, and K. |
