| 发明名称 |
MUTANT LYSENIN PORES |
| 摘要 |
The invention relates to mutant forms of lysenin. The invention also relates to analyte characterisation using lysenin. |
| 申请公布号 |
US2015068904(A1) |
申请公布日期 |
2015.03.12 |
| 申请号 |
US201314391660 |
申请日期 |
2013.03.15 |
| 申请人 |
OXFORD NANOPORE TECHNOLOGIES LIMITED |
发明人 |
Bruce Mark;Clarke James;Heron Andrew;Jayasinghe Lakmal;Wallace Jayne |
| 分类号 |
C07K14/435;G01N27/447;C12Q1/68 |
主分类号 |
C07K14/435 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A mutant lysenin monomer comprising a variant of the sequence shown in SEQ ID NO: 2, wherein the monomer is capable of forming a pore and wherein the variant comprises one or more modifications within the region of from about position 44 to about position 126 of SEQ ID NO: 2 which alter the ability of the monomer to interact with a polynucleotide. |
| 地址 |
Oxford GB |
