YEAST STRAIN FOR THE PRODUCTION OF PROTEINS WITH MODIFIED O-GLYCOSYLATION
摘要
Lower eukaryotic host cells have been recombinantly engineered to produce glycoprotein having human-like O-glycosylation. The glycoproteins are useful for the production of glycoprotein compositions with advantages for the production of human therapeutics.
申请公布号
EP2678440(A4)
申请公布日期
2015.03.11
申请号
EP20120749852
申请日期
2012.02.20
申请人
MERCK SHARP & DOHME CORP.
发明人
BOBROWICZ, PIOTRI;COOK, WILLIAM, J.;HAMILTON, STEPHEN;NETT, JUERGEN;STADHEIM, TERRANCE, A.;WILDT, STEFAN