发明名称 |
USE OF ANTI-DKK1 MONOCLONAL ANTIBODY FOR TREATMENT OF LIVER CANCER |
摘要 |
The invention provides a method of treating liver cancer comprising administering anti-DKK1 monoclonal antibody to a subject in need thereof. Anti-DKK1 monoclonal antibody can also be administered for preventing or ameliorating cancer metastasis and for neutralizing serum and tissue DKK1 in liver cancer patients. The use of anti-DKK1 monoclonal antibodies is based on the discovery of the upregulation of DKK1 in human liver cancer. |
申请公布号 |
EP2670435(A4) |
申请公布日期 |
2015.03.11 |
申请号 |
EP20120741908 |
申请日期 |
2012.01.18 |
申请人 |
THE UNIVERSITY OF HONG KONG |
发明人 |
NG LUI, OILIN, IRENE;TUNG, KWOKKWAN |
分类号 |
A61K39/395;A61P35/00;C07K16/18;C07K16/30;G01N33/574 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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