发明名称 ベンジリデンアミノグアニジンおよびヒドロキシグアニジンのメラノコルチン受容体リガンドとしての使用
摘要 <p>The present invention relates to the use of compounds of general formula (I) as ligands to the melanocortin receptors and/or for treatment of disorders in the melanocortin system: wherein X is H or OH; R1, R2, R3, R4 and R5 are the same or different and are selected from hydrogen, halogen, alkyl having 1 to 5 carbon atoms, electron donor groups such as alkoxy having 1-5 carbon atoms or hydroxy, electron acceptor groups selected from cyano, nitro, trifluoroalkyl or amide; alkylamino, benzoyloxy, nitroxy, phenyl or sulpho; and the pharmacologically active salts thereof.</p>
申请公布号 JP5683396(B2) 申请公布日期 2015.03.11
申请号 JP20110148414 申请日期 2011.07.04
申请人 发明人
分类号 A61K31/155;C07D317/58;A61K8/00;A61K8/43;A61K31/185;A61K31/275;A61K31/36;A61K51/00;A61P1/04;A61P1/14;A61P1/16;A61P1/18;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P5/00;A61P5/06;A61P5/10;A61P5/14;A61P5/30;A61P5/40;A61P7/00;A61P7/02;A61P7/04;A61P7/06;A61P7/08;A61P7/10;A61P9/00;A61P9/02;A61P9/04;A61P9/06;A61P9/08;A61P9/10;A61P9/12;A61P9/14;A61P11/00;A61P11/02;A61P11/06;A61P13/12;A61P15/00;A61P15/04;A61P15/06;A61P15/08;A61P15/10;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P17/08;A61P17/16;A61P19/02;A61P19/04;A61P25/00;A61P25/02;A61P25/04;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P25/36;A61P27/02;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P33/02;A61P33/10;A61P35/00;A61P35/04;A61P37/02;A61P37/04;A61P37/06;A61P37/08;A61P39/00;A61P39/02;A61P43/00;A61Q17/04;A61Q19/00;A61Q19/02;C07D317/62 主分类号 A61K31/155
代理机构 代理人
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