发明名称 Apparatus and method for aerosol delivery to the lungs or other locations of the body
摘要 This disclosure relates to an apparatus useful for the delivery of aerosols, such as those containing drugs, to the lungs or other locations in the body. The disclosure also relates to methods of administering an aerosol to the lungs or other locations in the body of a patient.
申请公布号 US8974771(B2) 申请公布日期 2015.03.10
申请号 US201012720341 申请日期 2010.03.09
申请人 Penn-Century, Inc. 发明人 Century Theodore J.
分类号 A61K9/12;A61M11/00 主分类号 A61K9/12
代理机构 Saul Ewing LLP 代理人 Saul Ewing LLP
主权项 1. An apparatus comprising: a reservoir in fluid communication with an outlet channel; a low pressure pump-inlet in fluid communication with the outlet channel; a high pressure pump in fluid communication with the low pressure pump-inlet; a high pressure pump-outlet in fluid communication with the high pressure pump, the high pressure pump-outlet having a switching valve, said switching valve having a delivery outlet; and an aerosolizer in fluid communication with the delivery outlet, the aerosolizer comprising an elongated sleeve member with a proximal end and a distal end, containing at the distal end an insert having an outer surface with a substantially helical channel surrounding the outer surface, and an orifice at an end wall thereof; wherein the apparatus supplies no gas to aerosolize liquid, and wherein when the reservoir contains a liquid, pressurized liquid flowing from the outlet channel to the orifice is unexposed to gas until it exits the apparatus via the orifice, and said pressurized liquid passes through the helical channel and through the orifice, at which point said pressurized liquid is aerosolized as it encounters ambient air at a pressure lower than a pressure of the pressurized liquid.
地址 Wyndmoor PA US
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