METHOD FOR FUNCTIONALISING SURFACE OF MAGNETIC NANOPARTICLES

摘要

FIELD: chemistry.SUBSTANCE: according to the method magnetic nanoparticles and glutaric dialdehyde are added to a polymer in a phosphate buffer under conditions of an alternating magnetic field, then, peptised and activated particles are three times washed with a phosphate buffer solution, depositing them under the influence of a constant magnet, the activated particles are mixed with an anti-analite solution for conjugation under conditions of the alternating magnetic field, after which the conjugate is washed three times by deposition-resuspension in the phosphate buffer solution, alternating the action of constant and alternating magnetic fields.EFFECT: obtaining strong functional conjugates which can serve as a basis for the creation of effective instrument-free systems for simplified diagnostic testing.4 ex