| 发明名称 | Fully humanized anti-HER2 antibody, preparation method and use thereof | ||
| 摘要 | The invention provides a fully human anti-HER2 monoclonal antibody, which has an amino acid sequence of heavy chain variable region as shown in SEQ ID NO: 6 and an amino acid sequence of light chain variable region as shown in SEQ ID NO: 8. The invention also discloses the nucleotide sequence encoding the antibody, the expression vector and the host cell comprising the nucleotide sequence, and the use of the antibody for manufacturing the medicament for the treatment of tumor. | ||
| 申请公布号 | US8974785(B2) | 申请公布日期 | 2015.03.10 |
| 申请号 | US201013579180 | 申请日期 | 2010.04.16 |
| 申请人 | Shanghai Biomabs Pharmaceuticals Co., Ltd. | 发明人 | Li Chuan;Tong Xin;Kan Ying |
| 分类号 | C07K16/00;C07K16/32;C07K16/30;A61K39/00 | 主分类号 | C07K16/00 |
| 代理机构 | Cesari and McKenna, LLP | 代理人 | Cesari and McKenna, LLP |
| 主权项 | 1. A fully human anti-HER2 antibody, having a heavy chain variable region amino acid sequence as shown in SEQ ID NO: 6 and a light chain variable region amino acid sequence as shown in SEQ ID NO: 8. | ||
| 地址 | Shanghai CN | ||