Method for producing a bioactive surface on the balloon of a balloon catheter

摘要

The invention relates to a method for producing a bioactive surface on the balloon (3) of a balloon catheter (1). According to said method, the surface of the balloon (3) is at least partially wetted with a first solution of an active substance (8) and the section of the surface of the balloon (3) wetted with the first solution of an active substance (8) is then wetted with a second, saturated solution of the active substance (28). The invention further relates to a balloon (3) of a balloon catheter (1) the surface of which is at least partially coated with an active substance (11), the coating (11) being homogeneous and brittle in the entire coated region.

主权项

1. A method for coating a surface of a balloon of a balloon catheter with an active ingredient, comprising the steps of:
a) producing an active ingredient layer, consisting of an active ingredient, as a lacquer-like coating across the outermost surface of the balloon by
aa) applying the active ingredient to the outermost surface of the balloon by wetting the surface of the balloon with a first solution comprised of the active ingredient and a first solvent with partial absorption of the first solvent by the balloon through the surface of the balloon;ab) drying the surface of the balloon wetted with the first solution; b) converting the active ingredient layer of step a) to a chalk-like coating with improved active ingredient release from the balloon by applying a second solution comprised of a second solvent and the active ingredient.