| 主权项 |
1. A compound of Chemical Formula 1, a positional or optical isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof: wherein R1 is selected from a group consisting of hydrogen, C1-C5 alkyl, haloalkyl, C1-C5 cycloalkyl and C1-C5 alkoxyalkyl; each of R2 and R7 is hydrogen; each of R3, R4, R5 and R6 is independently selected from a group consisting of hydrogen, fluoro, chloro, bromo, iodo, nitro, cyano, C1-C5 alkyl, hydroxy C1-C5 alkyl, C1-C5 alkoxy, C1-C5 alkoxy alkyl, halo C1-C3 alkyl, halo C1-C5 alkoxy, haloalkoxy C2-C5 alkenyl, C2-C5 alkenyl, alkynyl, carboxyl, C1-C5 alkylcarbonyl, C1-C5 alkoxycarbonyl, C1-C5 alkylcarbonylamino, C1-C15 alkylamino carbonyl, C1-C15 alkylsulfanyl, C1-C15 alkylsulfonyl, C1-C5 alkoxysulfonyl, C1-C5 alkylsulfamoyl, aryl, aryl C1-C3 alkyl, aryl C1-C5 alkoxy, aminosulfonyl, C1-C15 alkylamino, C1-C15 alkylaminosulfonyl, C1-C15 alkylsulfonylamino, C1-C5 alkylthio, C3-C7 cycloalkylsulfonylaminophenyl,or two selected from R3 through R6 form a 5- to 7-membered ring fused with an aryl group together with the carbon atoms to which they are bound and the ring includes 0-2 double bonds and contains 0-2 N, O or S atoms;
each of R8, R9, R10 and R11 is independently selected from a group consisting of hydrogen, fluoro, chloro, bromo, iodo, nitro, cyano, C1-C5 alkyl, C1-C5 alkoxy, halo C1-C3 alkyl, haloalkoxy C2-C5 alkenyl, C2-C5 alkenyl and alkynyl; and each of R12 and R13 is independently selected from a group consisting of hydrogen, C1-C5 alkyl, hydroxy C1-C5alkyl, C3-C7 cycloalkyl and halo C1-C5 alkyl, or R12 and R13 form a 5- to 7-membered ring together with the nitrogen atom which they are bound and the ring contains 0-2 N, O or S atoms or at least one substituent selected from a group consisting of hydrogen, hydroxy, hydroxy C1-C5 alkyl, C1-C5 alkoxy, C1-C5 alkoxy alkyl, halo C1-C5 alkyl, halo C1-C5 alkoxy and carboxyl. |
