摘要 |
(1) Compounds (I) where R'=F, Cl, Br, CH3 or CF3. R2 and R3=H (or together) -CH2- the dotted line in 6(7) position = opt. double bond. (2) Medicaments contng. (I). Ovulation inhibiting, cycle influencing, antiandrogenic, gonadotrophin influencing, antioestrogenic and/or antifertility properties. The antioestrogenic activity of 6alpha, 16alpha-dimethyl-4-pregnen-3beta-ol-20-one is 2 or 3 times as great as 6alpha,16alpha-dimethyl progesterone. 6alpha,16alpha-dimethyl-4-pregnen-3beta-ol-20-one. |