Method for detecting rhabdomyosarcoma using sample derived from body fluid

摘要

The present invention provides a method for detecting rhabdomyosarcoma comprising evaluating expression of at least one kind of miRNA selected from the group consisting of hsa-miR-1, hsa-miR-133a, hsa-miR-133b, and hsa-miR-206 in a sample derived from body fluid.

主权项

1. A method for detecting or diagnosing a rhabdomyosarcoma in a subject suspected of having a rhabdomyosarcoma comprising:
quantifying expression of hsa-miR-1 in a first sample which is derived from a body fluid that is obtained from the subject suspected of having a rhabdomyosarcoma, quantifying expression of hsa-miR-1 in a second sample which is derived from a body fluid that is obtained from a normal subject; and comparing expression of hsa-miR-1 in the first sample with expression in the second sample, wherein detecting or diagnosing a rhabdomyosarcoma is obtained when there is increased expression of hsa-miR-1 in the first sample with respect to the second sample, and wherein expression is detected by real-time PCR and wherein the increased expression is evaluated is evaluated by having a P of less than 0.08 in a statistical test.