Instrument for applying therapeutic cells, with distal portion for processing therapeutic cells

摘要

A tissue harvesting and processing apparatus comprises a body and a distally extending needle. The needle includes an aperture configured to receive tissue. A tissue cutting member is movable relative to the needle to sever a specimen from tissue protruding through the aperture. The tissue cutting member is further operable to mince the severed tissue specimen. The minced tissue may be mixed with a medical fluid component contained in a reservoir. A plunger may expel the medical fluid mixture from the needle. An applier tip may be coupled with the needle to facilitate administration of the medical fluid mixture at a target site in a patient. The needle may comprise a cannula with a needle adapter, which be removed from the cannula to allow the applier tip to be coupled with the cannula. The tissue cutting member may comprise a perforated disc or tube with inwardly projecting blades.

主权项

1. A tissue harvesting and processing apparatus, the apparatus comprising:
(a) a body; (b) a needle extending distally from the body, wherein the needle comprises a first lumen, wherein the needle defines a longitudinal axis, wherein the needle further defines an opening configured to receive prolapsed tissue, and wherein the first lumen is in communication with the opening; (c) a tissue cutting member disposed within the first lumen, wherein the tissue cutting member includes a mincing feature configured to simultaneously sever and mince tissue within the first lumen; and (d) a plunger member disposed within the first lumen proximally of the tissue cutting member, wherein the tissue cutting member is movable independently of the plunger member to mince a tissue specimen, and wherein the plunger member and the tissue cutting member are together movable to expel a mixture of tissue minced by the tissue cutting member with a medical fluid component through the opening.