Pelvic tissue support devices

摘要

A delivery system is provided that is adapted to treat various urological pelvic disorders, such as prolapse, incontinence, and the like. The delivery system can include at least one biologic loaded or otherwise provided with a bioactive agent. The biologic can comprise any drugs, hormones or steroids, stem cells, growth factors, proteins, and/or other bioactive agents to promote cell or tissue growth for the treatment and strengthening of organ walls or tissue. The biologic is generally adapted to controllably release the agent to the surrounding tissue or organ to provide a local and targeted delivery.

主权项

1. A biologic delivery system for treating pelvic disorders in a patient, comprising:
a biologic that is a particularized non-chemically crosslinked porcine dermis loaded with a bioactive agent selected from the group consisting of a growth factor and a hormone; a pelvic implant device adapted to support pelvic tissue of the patient and to deliver the loaded bioactive agent to a target tissue within the pelvic region of the patient, wherein the pelvic implant device is a pelvic sling constructed at least in part of a mesh material or a thin sheet, and the biologic is incorporated into or coated on the pelvic sling.